Piersicute de iulie august (19)

[Inaf78]

Infant with unusual food reactions (Case Presentation)

Melanie A Ruffner1, David N Finegold2, Andrew J MacGinnitie (andrew.macginnitie@childrens.harvard.edu)3

1.University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

2.Division of Genetics, Department of Pediatrics, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA

3.Division of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children’s Hospital of

Pittsburgh of UPMC, Piitsburgh, PA, USA

Correspondence

Andrew J MacGinnitie, Divison of Immunology,

Children’s Hospital of Boston, 300 Longwood Ave,

Boston, MA 02115, USA.

Tel: +011-617-919-2526 |

Fax: +011-617-731-0130 |

Email: andrew.macginnitie@childrens.harvard.edu

Received

8 February 2011; revised 9 March 2011;

accepted 8 April 2011.

DOI:10.1111/j.1651-2227.2011.02316.x

The Discussion and Diagnosis can be found on page 1394.

CASE

A previously healthy 6-month-old girl presented with a history

of unusual food reactions. She had been exclusively

breastfed except for a few instances when she had eaten rice

cereal without incident. Approximately 3 weeks before her

presentation in clinic, she had been fed approximately 15 g

of squash baby food. She ate the squash without apparent

difficulty, behaved normally, and napped for 1.5 h. At that

time, her mother found her in her crib covered in vomit and

mucous, lethargic and difficult to arouse. However, within

another hour the girl began to behave normally again and

the family did not seek medical attention.

Approximately 1 week prior to her presentation, the

family tried to introduce bananas. In this case, she ate

the full jar of baby food (70 g) and she had a similar

reaction: about 1.5 h after ingesting the bananas, she had

recurrent vomiting which progressed to vomiting mucous

and eventually dry heaves. Again, she became lethargic,

limp, less interactive, and difficult to arouse. This lasted

for approximately 8 h at which time she began to show

improvement. The parents called the pediatrician and

were advised to continue supportive care at home. They

also halted introduction of new foods, continuing to feed

breast milk and rice cereal as they had been doing previously.

Apart from these two incidents, the patient had not had

other episodes of significant vomiting or lethargy. She was

born at term at 7 pounds 8 ounces to a gravida 2 para

1 fi 2 mother with delivery at term by Cesarean section

because of prior Cesarean. She breast fed well and development

was normal. Her only significant past medical history

was gastrointestinal reflux for which she took ranitidine,

and mild eczema that was well controlled on hydrocortisone

1% cream. There was no family history of similar food

intolerance.

On examination, she was afebrile with normal heart and

respiratory rates. Weight was at the 75th percentile and

length fell between 75th and 90th percentiles. HEENT

exam, and examination of heart, lungs, abdomen, skin and

neurological system showed no abnormalities.

 

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[Inaf78]

Pediatr Allergy Immunol. 2011 Mar;22(2):186-95. doi: 10.1111/j.1399-3038.2010.01125.x. Epub 2011 Feb 1.

 

Sensitization profiles to purified plant food allergens among pediatric patients with allergy to banana.

 

Palacin A, Quirce S, Sanchez-Monge R, Bobolea I, Diaz-Perales A, Martin-Muñoz F, Pascual C, Salcedo G.

 

 

Source

 

Unidad de Bioquímica, Departamento de Biotecnología, ETS Ingenieros Agrónomos, Universidad Politécnica, Madrid, Spain.

 

 

Abstract

 

Banana fruit allergy is well known, but neither immunoglobulin E recognition patterns to purified plant food allergens nor true prevalences of putative banana allergens have been established. This study aimed to characterize #946;-1,3-glucanase and thaumatin-like protein (TLP) as banana allergens, testing them, together with other plant food allergens, in 51 children with allergic reactions after banana ingestion and both positive specific IgE and skin prick test (SPT) to banana. Banana #946;-1,3-glucanase and TLP were isolated and characterized. Both banana allergens, together with kiwifruit TLP Act d 2, avocado class I chitinase Pers a 1, palm pollen profilin Pho d 2 and peach fruit lipid transfer protein (LTP) Pru p 3, were tested by in vitro and in vivo assays. Banana #946;-1,3-glucanase (Mus a 5) was glycosylated, whereas banana TLP (Mus a 4) was not, in contrast with its homologous kiwi allergen Act d 2. Specific IgE to both banana allergens, as well as to peach Pru p 3, was found in over 70% of sera from banana-allergic children, and Mus a 4 and Pru p 3 provoked positive SPT responses in 6 of the 12 tested patients, whereas Mus a 5 in only one of them. Both peptidic epitopes and cross-reactive carbohydrate determinants were involved in the IgE-binding to Mus a 5, whereas cross-reactivity between Mus a 4 and Act d 2 was only based on common IgE protein epitopes. Profilin Pho d 2 elicited a relevant proportion of positive responses on in vitro (41%) and in vivo (58%) tests. Therefore, Mus a 4 and LTP behave as major banana allergens in the study population, and profilin seems to be also a relevant allergen. Mus a 5 is an equivocal allergenic protein, showing high IgE-binding to its attached complex glycan, and low in vivo potency.

 

 

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[Inaf78]

in fine, exista multe articole de acest gen, multe cu informatii de super amanunt.

daca e cineva interesat se pot citi multe pe Pubmed-Medline:

http://www.ncbi.nlm.nih.gov/pubmed?term=banana%20allergy

 

oricum si aici sunt multe de interpretat...

 

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M si R

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http://bebeinfo.webs.com/

 

 

[Inaf78]

World J Pediatr. 2012 Nov;8(4):317-20. doi: 10.1007/s12519-012-0375-z. Epub 2012 Nov 15.

 

Sensitization to food allergens in Iranian children with mild to moderate persistent asthma.

 

Farjadian S, Moghtaderi M, Kashef S, Alyasin S.

 

 

Source

 

Allergy Research Center, University of Medical Sciences, Shiraz, Iran.

 

 

Abstract

 

BACKGROUND:

 

Asthma is the most common chronic respiratory disease in childhood. The clinical presentation of asthma may worsen after food allergen ingestion in sensitized patients. To avoid nonspecific dietary restrictions in children with asthma, laboratory-based advice about foods is potentially helpful. The purpose of this study was to determine food sensitization in children with asthma.

 

METHODS:

 

Seventy-nine children with mild to moderate persistent asthma were included in this study. Commercial food allergens including cow's milk, egg white, almond, potato, and soybean were used in skin prick tests. Specific IgE to 20 common food allergens was also measured in serum.

 

RESULTS:

 

Twelve (15.2%) of the patients had a positive skin prick test to at least one of the five food extracts. Sensitization was detected by skin prick tests to cow's milk and egg white (each 6.3%), almond (3.8%), potato (2.5%) and soybean (1.3%). Specific IgE levels #8805;0.35 kAU/L were detected in the serum of 47% of the children with asthma. The most common food allergens were cow's milk (26.6%), hazelnuts (25.3%), wheat flour (15.2%) and egg white (12.6%). Patients with a history of at least one hospital admission due to asthma attack had a higher rate of sensitization to egg.

 

CONCLUSIONS:

 

In our study, food sensitization was frequent in Iranian children with asthma. Although clinical food allergy could not be evaluated because food challenge tests were not used in our study, skin prick tests and serum-specific IgE to common food allergens might be helpful in identifying children with food sensitization.

 

 

 

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[Inaf78]

http://www.ncbi.nlm.nih.gov/pubmed?term=potato%20allergy

 

 

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http://bebeinfo.webs.com/

 

 

[Inaf78]

Iran J Immunol. 2012 Mar;9(1):32-8. doi: IJIv9i1A2.

 

Specific IgE to Common Food Allergens in Children with Atopic Dermatitis.

 

Moghtaderi M, Farjadian S, Kashef S, Tavakoli M, Alyasin S, Afrasiab M, Orooj M.

 

 

Source

 

Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, e-mail: kashefs@sums.ac.ir.

 

 

Abstract

 

Background: Atopic dermatitis is a major public health problem, often starting in early childhood and sometimes followed by other allergic diseases. Although hypersensitivity to foods is assumed to play an essential role in the development of atopic dermatitis in some patients, little is known about common food allergens in Iranian children with atopic dermatitis. Objectives: This study was designed to identify probable food allergens in Iranian children with atopic dermatitis and find the relationship between food sensitization and the severity of atopic dermatitis. Methods: This study included 90 children aged 2-48 months with atopic dermatitis. Skin prick tests for cow's milk, hen's egg, almond, potato and soybean were done. Serum specific IgE to 20 food allergens was also screened. Results: Among children with atopic dermatitis, the frequency of food sensitization was 40% by skin prick test and 51% by food-specific IgE. Children with atopic dermatitis were most commonly sensitized to cow's milk (31%), hen's egg (17.7%), tree nuts (17.7%), wheat (12.2%), potato (11.1%), tomato (8.8%) and peanut (8.8%). In 42 children with moderate to severe eczema, sensitivity to food allergens was 78.5% by skin prick test and 88% by serum specific IgE evaluation. Conclusion: Our results showed that cow's milk, hen's egg and tree nuts were the most common food allergens in Iranian children with atopic dermatitis. Sensitization to foods was much higher in patients with moderate to severe atopic dermatitis. Determining specific IgE in children with atopic dermatitis can be helpful in managing these patients.

 

 

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M si R

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http://bebeinfo.webs.com/

 

 

[Inaf78]

ce e de retinut, este frecventa cu care apar alergiile la diverse alimente, ordinea lor: lapte de vaca, oua, alune, grau, cartof, rosii, arahide.

 

 

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M si R

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http://bebeinfo.webs.com/

 

 

[Inaf78]

mai vb cand ajung acasa.

o zi frumoasa tuturor!

 

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M si R

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http://bebeinfo.webs.com/

 

 

[Laura32]

Ina , esti fantastica . Ai un mare de la mine . O sa merg la spital de stat pana la urma . Acum sunt in "cercetari" sa vedem daca mai apare ceva.

 

Mami de [copil] Andrei ( 3 Iulie 2012)

 

 

 

 

 

[balanta_tm]

fetelor, in bagajul de cala pot sa duc cu mine fiolele de fier tot'hema, un sirop stodal si chestii de astea? multumesc!